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Principal Scientist Epithelial Biology


Cambridge, MA
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Job Details

Job Title Principal Scientist Epithelial Biology

JobID 1049181-1852

Location: Cambridge, MA

Description *About Pfizer*

A career at Pfizer offers opportunity, ownership and impact.All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

*Role Description*

We are seeking an innovative epidermal biologist to join a creative and fast-paced Inflammation and Immunology team at Pfizer. The successful applicant will have experience in human skin culture systems with expertise in immunology and innate immunity. The incumbent will spearhead a vigorous research program aimed at elucidating cellular and molecular pathways that are relevant to the pathophysiology of inflammatory and autoimmune disorders of the skin. This role will provide scientific and technical leadership to enable the development of topical and systemic therapeutics to address significant unmet medical need in dermatology.


*Develop and execute in vitro human skin model systems to elucidate cellular and molecular mechanisms of action for potential therapeutic candidates.*Identify, trouble-shoot, and optimize relevant assay systems, technologies, and readouts.*Build group capabilities in 3D culture systems.*Independently design experiments, interpret and track results. *Organize, summarize, and present data.*Work collaboratively with project teams


*PhD in Immunology or related discipline and 2 years of Postdoctoral or equivalent Industrial experience in skin biology*Experience with standard immunology techniques and skin culture systems is required. *Experience with molecular techniques and CRISPR/Cas9 desirable.*Expertise with imaging techniques, including high content analysis, a plus.*Highly motivated, creative, and interactive.*Effective oral and written communication skills*Strong history of publication in peer-reviewed journals

*EEO & Employment Eligibility*

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

*Principal Scientist Epithelial Biology*
*Cambridge, Massachusetts*

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