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Scientist, Immunotoxicology (non

Pfizer


Location:
Groton, CT
Date:
11/21/2017
2017-11-212017-12-22
Pfizer
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Job Details

Immunotoxicology Center of Emphasis (CoE) in Drug Safety Research & Development (DSRD) is a global resource focused on supporting assay development and sample testing for non-clinical and clinical studies in the areas of hypersensitivity, immunomodulation, and immuno-oncology. These efforts support multiple Therapeutic Areas in the risk assessment process, regulatory filings, and investigative studies to de-risk compounds during all stages of drug discovery.







The successful candidate will be a highly motivated scientist with a solid background in flow cytometry and immunology. The qualified candidate will primarily work in our immunophenotyping flow cytometry lab and will be responsible for independently running flow cytometry assays to support safety and efficacy assessments for non-clinical studies. In addition, the candidate will support immunoassays to evaluate aspects of immunomodulation, immuno-oncology and hypersensitivity. The candidate will have a desire to build on their knowledge of flow cytometry and learn new technologies and methods.







**ROLE RESPONSIBILITIES**







+ Develop and perform multicolor flow cytometry assays for samples from various species.



+ Perform instrument QC on a daily basis, trouble shoot problems, and build and modify machine configurations, as needed.



+ Characterize and qualify reagents, including antibody panels and titers.



+ Perform data analysis using FACSDiva and FlowJo applications.



+ Have knowledge and experience working with LIMS (laboratory and information management system).



+ Demonstrate strong attention to detail and trouble shooting skills, data interpretation, and the ability to work independently and collaboratively across lines.



+ Interpret and summarize experimental data and report summaries in team meetings, as needed.



+ Train other users on all aspects of flow cytometry including experimental planning, data acquisition and analysis.



+ Be familiar with emerging technologies and desire to expand knowledge past traditional flow cytometry.







**QUALIFICATIONS**







+ BA or BS degree with 5+ years or a MA with 4+ years flow cytometry experience in an appropriate scientific area and a degree in immunology, cell biology, molecular biology, microbiology, or biochemistry.







**PREFERRED QUALIFICATIONS**







+ Understanding of flow cytometry fundamentals and experience with analyzers including: BD FACSCanto, BD LSRII.



+ Expertise in developing and running 8+ color flow cytometry panels.



+ Technical expertise with immunoassays (ELISA, MSD, Luminex), cell-based assays (proliferation, cytotoxicity, receptor binding, phagocytosis, ELISpot, and ADCC/CDC assays) and cell culture are desired.



+ Software proficiency: FACSDiva, FlowJo, GraphPad Prism, and Microsoft Office.







**EEO & Employment Eligibility**



Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.







**Sunshine Act**



Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.







Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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