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Scientist (non


Pearl River, NY
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Job Details

Job Title Scientist (non

JobID 1619498

Location: Pearl River, NY

Description We are seeking a highly motivated scientist to join the Oncology Therapeutic Discovery Group in Pfizer's Oncology Research Unit. The successful applicant will assist in supporting reagent generation for our functional genomics screening platforms and provide weekly cell culture and assay support. The research scientist will be asked to provide support for shRNA/CRISPR reagent generation for Worldwide R&D projects that include:

-Providing cell culture, molecular biology cloning support for shRNA/CRISPR vector construction

-Providing weekly assay and data analysis support for target validation and screens

**Role Responsibilities**

The successful candidate will work independently as part of a research team that is focused on generating reagents for functional genomics screens and target validation in the OTD department. He/she will also provide weekly assay development and cell culture support for a number of different assay formats.

+ Provide molecular biology support to generate vector specific shRNA and/or CRISPR clones to support WRD projects

+ Track and inventory all shRNA/ CRISPR sequencing results for all new clones and library pools

+ Provide liquid handling support for 96 well /384 well plate formatted high throughput assays

+ Perform phenotypic and functional assays and screens

+ Provide and manage reagent inventories for compound, shRNA, and CRISPR library reagents

The candidate is expected to:

+ Work independently to perform and deliver high quality functional genomics reagents on a weekly basis.

+ Support, execute, and analyze/interpret experiments related to different assays and formats.

+ Present research results and discuss methods at weekly/monthly group meetings

+ Contribute to building a culture that embraces scientific innovation


B.S. degree with a minimum 6 years' experience working in industry

+ Knowledge and experience using automated liquid platforms such a Janus/Biomek or Tecan is required

+ Knowledge and experience in supporting mammalian cell culture is required

+ Experience in performing, optimizing, and analyzing assay data using 96/384 well microtiter assay formats is required

+ Experience with High Content imaging of FACS based cell analysis experience not necessary but beneficial

**Additional Offer Details**

+ Grade: 6

+ Eligible for Employee Referral Bonus

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

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