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Scientist (non


Pearl River, NY
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Job Details

We are seeking a highly motivated non-PhD level scientist with a strong background in oncology and/or immunology for a Scientist position within the Oncology Therapeutics Discovery Group. This group contributes to the identification and validation of novel Oncology targets to fuel the drug discovery pipeline.


+ Participate in immuno-oncology target validation efforts

+ Design and execute studies to investigate target biology, dissect potential mechanism of action, and elucidate immune response.

+ Prepare and analyze tissue samples for immune modulation by multi-color flow-cytometry and Luminex /ELISA-based assays.

+ Analyze and interpret data, troubleshoot results independently or with minimal supervision.

+ Present data and communicate research results among the team, record experimental protocols and results in an accurate and timely manner.

+ Attend team meetings and deliver well-prepared presentations. Participate actively in team/group discussions.


+ Bachelor's degree in Biology or related subjects with 6 plus years' laboratory experience in an industrial or academic setting; preferentially master's degree in cell biology or related field with at least 5 years' experience in an industrial or academic setting

+ Track record of successful contribution to research projects leading to advancement of projects

+ Proven ability to deliver consistent, reproducible, scientifically rigorous results.

+ Significant experiences with an standard molecular, cell biology, and immunology methods

**Technical requirements:**

+ Extensive cell culture expertise with both primary and immortalized cells. Experience with genetically modifying and engineering cell lines (by siRNA, CRISPR/Cas9 and lentiviral infections), 2D and 3D proliferation assays (Incucyte, Celigo, soft agar, Matrigel), cell death assays.

+ Immunology techniques such as PBMC and T cell isolation from blood/spleen/tumors, T cell activation, cytokine ELISA, ELIspot, Luminex. Proficiency in multi-color flow-cytometry, panel design and downstream data analysis.

+ Standard cell and molecular biology techniques such as western blotting, immunoprecipitation, immunofluorescence, microscopy, ELISA.

+ Proficiency with standard office and scientific software (Powerpoint, Excel, GraphPad Prism, FlowJo).

+ Strong ability to work independently, efficiently and productively in a fast-paced, highly collaborative and diverse team environment. Excellent organization and planning skills, high standards, motivated with a strong work ethic. Excellent written and oral communication and presentation skills in English.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**Other Job Details:**

+ Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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