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Scientist (non


San Francisco, CA
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Job Details

We are seeking a highly motivated scientist with experience in murine models of immune-oncology or immunology to join the immunology group at Rinat, a Pfizer biotech research until in South San Francisco. They will contribute to the discovery and research and development of innovative, protein-based immune-oncology therapeutics. The candidate will design and execute in vivo studies of immune-targeting in both murine and/or humanized mouse tumor models.

**Education and Experience**

+ BS in biological sciences with 6+ years' of experience, or MS with 5+ years', in industrial or academic setting

+ Biology degree specializing in immunology, or cellular and molecular biology preferred

+ Prior experience in the fields of molecular biology, immunology, and/or cancer biology highly preferred

+ Experience in maintaining a mouse colony, and with tissue necropsy is preferred

+ Hands on experience with syngeneic and xenograft mouse models of cancer including sub-cutaneous tumor implantation and/or orthotopic tumor models, tumor imaging measurements, i.v. or i.p. drug dosing, survival analysis.

+ Experience with PK and PD studies is highly desired

+ Proficiency with tissue harvest and cell dissociation is strongly preferred

+ Technical expertise with mammalian cell culture immune cell functional assays, multi-color flow cytometry, cytokine release, cytotoxicity and proliferation assays strongly preferred, ELISA, MSD or Luminex is preferred.

+ Experience with analysis software such as FlowJo, Graph Pad Prism, Excel is required.

+ Must be highly motivated with excellent organization and planning skills.

+ Must be willing to learn and adopt new experimental techniques.

+ Experience with basic molecular biology techniques, cell binding, transfection and lentiviral transduction is highly desirable.

+ A willingness to learn and adopt new experimental skills as needed is essential.

+ Ability to work with laboratory rodents for extended time.

+ Very good record-keeping of studies using electronic lab note book

+ Excellent verbal and written communication of results to manager and other team members in the group.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**Additional Offer Details**

Grade: 6

Additional Location Information: South San Francisco, CA

Eligible for Employee Referral Award

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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