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Scientist Pharmacology (Non


Cambridge, MA
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Job Details

The Pfizer Inflammation & Immunology (I&I) research unit aims to develop novel therapeutics to treat autoimmune and inflammatory diseases. The successful candidate for this position will conduct Pharmacology studies using in vivo animal model studies, ex vivo sample analysis and in vitro assays. The position is based in Kendall Square, Cambridge, MA but may require supporting studies at other Pfizer's sites as necessary.

**Job Focus**

Highly motivated individual to work in a challenging environment within the preclinical pharmacology group. As part of this team, this person will be supporting in vivo studies and analyzing samples obtained from these studies. Responsible for conducting and managing in vivo studies to determine the efficacy of both small molecule and biotherapeutic approaches. The evaluation and development of new technologies, biomarkers and in vivo models are key components of this position.


+ Plan and conduct of in vivo studies in support of Inflammation & Immunology therapeutic portfolio

+ Formulation of compounds and administration of drugs and experimental compounds by various routes

+ Collection of blood and various tissues

+ Scoring of study animals

+ Ability to learn and conduct other animal-related techniques

+ Ex vivo analysis of animal samples

+ Maintaining well-organized records and documentation

+ Data entry and analysis


+ M.Sc. or B.Sc. degree in physiology, pharmacology, or related biological science

+ B.Sc. degree with 6+ years or M.Sc. degree with 5+ years' experience

+ Experience working with small laboratory animals, preferably in a biotech or pharmaceutical environment

+ Well established hands-on experience with rodent in vivo dosing and handling techniques

+ Understanding of immunology or cell biology

+ Experience with animal models of autoimmunity and/or inflammation is desirable

+ Good organizational and communication skills, ability to focus attention to details

+ A high degree of flexibility, and a willingness and ability to work as a team member

+ Weekend work may be required

Technical expectations

+ Design and conduct experiments to support the mechanistic and disease biomarker discovery for in vivo models

+ Planning, coordination and execution of in vivo and ex vivo pharmacology studies in rodent models

+ Experience with small animal handling procedures, injections, oral dosing

+ Experience in tissue dissection and tissue preparation for histology, RNA, and protein analysis

+ Experience in molecular biology techniques such as ELISA, FACS, TLDA and RT-PCR, CBA and Luminex assays

+ Analyzing and presenting data to individuals and in group settings

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**Other Job Details:**

+ **Relocation is not available.**

+ Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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