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Senior Associate Scientist, Assay Development


Andover, MA
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Job Details

The Senior Associate Scientist will be responsible for the design, trouble shooting, qualification and conduct of the ligand-binding assays to support biotherapeutic programs. Deliver concentration and immunogenicity data to PDM BioTX principal investigators and other partners. Advance bioanalytical capabilities to improve efficiency, cost effectiveness and appropriateness of assay for discovery and development stage assets.


The incumbent will design, develop and implement ligand-binding assays (e.g. ELISA, MSD, Gyrolab) to measure protein concentration of drug and/or biomarker and detect the presence of anti-drug antibody in a fast paced and dynamic environment. Perform data analysis and interpretation and draw conclusions regarding progress and results of work, utilizing the data for appropriate decision making. Gather input from colleagues, literature, and additional resources to assist in project advancement.


+ BSc with at least 2-4 years relevant experience, with a focus on ligand binding assay development or MSc with 0-2 years relevant experience with a focus on ligand binding assay development.

+ Industry experience with a focus in biotherapeutics and a strong record of scientific achievement; excellent communication skills.

+ Proven track record in the area of biotherapeutics bioanalysis with understanding of a broad range of bioanalytical platforms. Proven presentation skills.

+ Knowledge and hands-on experience developing ligand-binding assays, utilizing various platforms and demonstrated analytical problem solving skills.

+ Ability to author technical documents such as data summary reports and analytical procedures. Collaborative skills and effective partnering skills in a complex, multi-discipline organizational model.

+ Proven ability to generate high quality data against challenging time lines

+ Ability to communicate across site and discipline to enable maximum impact of bioanalytical science.

+ Strong organizational and time management skills in order to balance working on multiple projects.

+ Broad understanding and skill in areas of bioanalytical laboratory techniques for biotherapeutics (knowledge of ligand-binding assays is essential; skills in other areas such as RT-PCR, digital PCR, cell-based assays and/or reagent characterization is a plus)

+ Knowledge of biotherapeutic structure, pharmacology, disposition and immunogenicity and the impact on assay selection.


+ Experience working with Large Molecules or Proteins in a biotherapeutics environment.

+ Broad understanding of Flow Cytometry and/or LCMS.


+ **Last Date to Apply for Job: February 26, 2018**

+ Additional Location Information: Andover, MA

+ Eligible for Employee Referral Bonus: Yes

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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