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Senior Associate Scientist, Novel Delivery Technologies

Pfizer


Location:
Andover, MA
Date:
09/22/2017
2017-09-222017-10-21
Job Code:
1613245
Pfizer
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Job Details

Job Title Senior Associate Scientist, Novel Delivery Technologies

JobID 1613245

Location: Andover, MA

Description Role Summary The incumbent candidate will be responsible for developing, evaluating and characterizing bioconjugates (protein conjugates, polymer conjugates, targeted nanomedicines) and other novel drug delivery formulations/devices for the delivery of diverse biotherapeutic modalities including (but not limited to) protein candidate molecules, vaccines, gene medicine and cell-based therapies, and other targeted delivery strategies. This individual functions cooperatively as a bioconjugation chemist and drug delivery scientist and is responsible for working in a team-based environment to meet project deadlines. The incumbent displays strong technical knowledge in various aspects of analytical chemistry, organic chemistry, and protein chemistry, with a drive to learn new techniques while working at the laboratory bench. Incumbent must have the scientific commitment and strong desire to make impactful scientific and technical contributions within the Pharmaceutical Research & Development team and the respective project teams.



Role Responsibilities



+ Hands-on experimentation towards the preparation of innovative drug delivery solutions including, but not limited to, bioconjugates composed of proteins, peptides, biopolymers and other biomolecules

+ Develop purification methods for the prepared samples and develop analytical methods to characterize the same and product-related variants and impurities. Comfortable with troubleshooting process, formulation and analytical challenges.

+ Utilize chromatographic, biophysical and other analytical methods for characterization in order to fully understand quality attributes for early research studies

+ Manage laboratory, including procurement of proteins and reagents, organizing and maintaining inventories, and monitoring stability samples

+ Data management, including notebook keeping, processing of data, compiling figures for presentations and writing reports

+ Present scientific results to team members and to larger diverse audiences



**Basic Qualifications**



+ MS with 0-2 year(s) relevant academic or pharmaceutical laboratory experience or BS/BA with 2-4 years relevant laboratory experience

+ Strong working knowledge in chemical synthetic reactions and reagents is essential

+ Hands on experience with protein, peptide and/or oligonucleotide chemistries is essential



**Preferred Qualifications**



+ Expertise in protein and peptide analytical and purification techniques such as Reverse Phase HPLC/UPLC, SEC, Ion-Exchange, HIC, Affinity chromatography, AFFF-MALS, BIAcore, SDS-PAGE, Capillary Electrophoresis, ELISA, LC-MS and/or other methods

+ Experience with conjugation chemistry, linkers and techniques is highly recommended

+ Some experience with polymers/biopolymers (PLA/PLGA, PEG, oligosaccharides, fatty acids, etc.) or with drug delivery technologies (nanoparticles, ADCs, hydrogels, liposomes, etc) is a plus

+ Excellent interpersonal skills and ability to work with others in a dynamic and highly collaborative environment is essential



**Additional Offer Details:**



+ **Last Date to Apply for Job: November 14, 2017**

+ **This job is Pfizer Exempt US Grade: 004**

+ Location: Andover, MA



**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.



**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.



A career at Pfizer offers opportunity, ownership and impact.



All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.



Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.


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