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Senior Scientist, Integrative Metabolism


Cambridge, MA 02139
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Job Details

**Company Overview**

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.


Within the Internal Medicine Research Unit (IMRU), one of the Metabolism group's key focuses is identifying novel therapies to improve metabolic homeostasis in patients suffering from cachexia across various chronic illnesses like cancer and heart failure. Our goal is to build an exciting team focused on deep mechanistic understanding of energy metabolism in cachexia, including tumor metabolism which is relevant to cancer cachexia. The scientific focus of this role is to identify critical metabolic pathways in cachexia that are important for reversing weight loss (adipose and muscle) and anorexia using rodent in vivo techniques in conjunction with human tissue/ cell models with the goal of developing effective therapies. Understanding of whole body energy metabolism is essential; experience in tumor biology would be valuable but not required. In addition to drug discovery interests, publication in high-impact journals and presentation of research is encouraged. The candidate will have daily interactions with a team of creative and innovative scientists in a supportive environment for rigorous scientific and drug development training. Strong self-motivation, excellent communication interpersonal skills, and the ability to work independently and as part of a team is essential.


+ apply scientific and technical expertise to drug discovery programs to impact the future of new drug candidate development

+ conceptualize and design experiments

+ organize and conduct in vivo/ ex vivo/ in vitro studies independently (including preparation, data collection, interpretation, and presentation)

+ maintain awareness of scientific and technical developments in field

+ author manuscripts for quality publications in top-tier journals.

attend and present at international meetings and collaborate across groups in the research unit.


+ PhD with a minimum of 2 years of post-doc experience, with a successful track record of scientific achievements through scientific publications and presentations. Experience in whole-body and/ or tumor metabolism.

+ Possess strong written/verbal communication skills and ability to effectively collaborate with scientists working in other disciplines including chemistry, drug metabolism, drug safety.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**Additional Offer Details:**

+ **Last Date to Apply for Job:** January 1, 2018

+ **This job is Pfizer Exempt (US/PR) Grade:** 008

+ Eligible for Employee Referral Bonus: yes

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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