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Senior Scientist, Oncology In Vivo Pharmacology


Pearl River, NY
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Job Details

Job Title Senior Scientist, Oncology In Vivo Pharmacology

JobID 1048062-1852

Location: Pearl River, NY

Description *About Pfizer*

A career at Pfizer offers opportunity, ownership and impact.All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

*Role Description*

A Senior Research scientist position for a candidate with a strong background in Biology including tumor immunology, animal models, cancer biology, tissue culture, imaging and pharmacology with in vivo experience in small mammals (mice/rats) is immediately available. In vivo efficacy studies using allograft, syngeneic, xenograft, GEMM and PDX models will be employed in order to determine the in vivo efficacy of lead immuno-therapy molecules identified by the research teams in the Oncology department. The Sr. Scientist will develop a solid understanding of the biology for each of the programs being supported by the immune tumor biology groups. The candidate must function as an integral member of the in vivo biology team, responsible for all aspects of in vivo testing in a coordinated manner with other members of the in vivo team. The Sr. Scientist in addition to conducting the in vivo studies will work closely with their manager and be also responsible for supporting and overseeing the team's workflow, developing new models, analyzing data and helping to integrate in vivo information into the design of new studies with the goal of advancing immunotherapeutic leads into Development track compounds and beyond.


* Demonstrate a high level of independence in performing in vivo experiments, analyzing data, and drawing conclusions regarding experimental progress and results of work. Good communication regarding experiment execution and analysis with supervisor and colleagues. * Contribute to the design and performance of in vivo experiments with patient-derived cancer models, syngeneic and cell line based cancer models to support immune based therapies. Flow cytometry and live animal imaging experience required. * Perform meticulous record keeping and generate scientific reports to support preclinical cancer drug development. * Query molecular databases to identify experimental models that have desired genotypes, cancer target expression, or desired growth phenotypes. * Comply with Pfizer policy, IACUC regulations, animal use protocols, experimental study design protocol, and standard operating procedures. * Possess excellent time-management skills and manage experiments in several projects concurrently. Manage and supervise workflow of the immune-therapy in vivo group. * Accommodate a flexible schedule that may include some weekend responsibilities to ensure optimization of in vivo pharmacology workflow. * The candidate must function as an integral member of the in vivo biology team, responsible for all aspects of in vivo testing in a coordinated manner with other members of the team. * Maintain familiarity with current and emerging technologies through reading and understanding scientific and technical literature enabling the use of new and improved procedures in the laboratory.


* BS/MS in biological sciences, 10 years of experience conducting in vivo research with rodents. Ph.D. including post-doctoral training with 0-5 years of experience including rodent research as major aspect of thesis or post-doctoral experience.* No allergies to animals restricting work in the animal vivarium.* To accommodate animal studies weekend or holiday hours may be required.PHYSICAL/MENTAL REQUIREMENTS No allergies to animals restricting work in the animal vivarium.NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS To accommodate animal studies weekend or holiday hours may be required.

*EEO & Employment Eligibility*

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

*Senior Scientist, Oncology In Vivo Pharmacology*
*Pearl River, New York*

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