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Senior Scientist, Purification Process Development


Andover, MA
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Job Details

A Senior Scientist of Purification Process Development position is available in the Bioprocess R&D group in Andover, MA. The successful applicant will have experience in laboratory research, and a desire to continue in a laboratory-focused role. This position will join a larger team of scientists across multiple sites focused on developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials. The Senior Scientist will be responsible for working with fellow scientists to develop robust, efficient, scalable strategies for improving process performance.


+ Small-scale studies, and pilot plant and manufacturing downstream purification studies.

+ Develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes.

+ Support process validation, quality by design, regulatory approaches, and quality systems.

+ Prepare internally reviewed technical reports, make oral presentations to scientists and management, and publish externally.

+ Executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes.

+ Endorse change to business infrastructure to ensure pipeline, legacy and technology success.


+ Ph.D in a biological or engineering discipline (Biotechnology, Biochemistry, Chemical/Biochemical Engineering, or equivalent) with 0-3 years of industry experience or MS Degree with 3-5 years of industry experience with same educational background

+ Experience in recombinant protein purification process development, technology transfer and/or bioprocess manufacturing required.

+ Demonstrated ability to drive for results and drive innovative research programs independently.

+ Understanding of protein chemistry and protein analytics, including the recent scientific literature, is required.

+ Applicants should be organized, self-motivated, and capable of working independently as well as in a collaborative environment.

+ Strong oral and written communication skills.

+ Strong analytical and computer skills are required.


+ Diverse work experience recovering recombinant proteins from mammalian and microbial/yeast cultures.

+ Experience transferring biologics processes to pilot plants or manufacturing organizations, and knowledge of data acquisition and controls systems in these environments is desirable.

+ Experience taking a late-stage project through process validation and commercialization is desired.

+ Sound understanding of statistical experimental design and analysis is a benefit.

+ Strong working knowledge of the drug development process for progression of a biological candidate.

**Other Job Details:**

+ **Last Date to Apply for Job: April 9, 2018**

+ Additional Location Information: Andover, MA

+ Eligible for Employee Referral Bonus: Yes

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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