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Senior Scientist, T


South San Francisco, CA
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Job Details

Job Title Senior Scientist, T

JobID 1040455-1852

Location: South San Francisco, CA

Description *About Pfizer*

A career at Pfizer offers opportunity, ownership and impact.All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere.Our colleagues have the opportunity to grow and develop a career that offers both individual and company success;be part of an ownership culture that values diversity and where all colleagues are energized and engaged;and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry,is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

*Role Description*

We are seeking to hire an enthusiastic and team-oriented scientist with demonstrated expertise in cancer immunotherapy to lead, or collaborate in teams, to explore the preclinical biology around allogeneic CAR T cell therapy and modifications of CAR Ts for solid tumor micro-environments.


Primary Duties:*Design and execute in vitro and in vivo preclinical studies to understand allogeneic CAR T activity, GvHD and rejection *Contribute to a collaborative group effort to consider next generation allogeneic CAR technology*Contribute to a collaborative group effort to choose CAR T modifications or evaluate drug combinations to enhance CAR T activity in resistant solid tumor models*Collaborate with technology development group to inform future manufacturing process improvements for allogeneic CARs*Participate in collaboration on CAR T targets with Cellectis and Servier*Stay abreast of latest scientific and technology advancements in the field*Contribute to a culture that embraces continuous learning and development


*PhD with 2-5 years post-doctoral training preferred with significant relevant experience in cancer immunotherapy, preferably in the area of T cell therapy*Experience of target validation and candidate selection is essential *Knowledge of cellular and molecular immunology with an emphasis on T cell immunology experience*Ability to design and execute in vitro and in vivo cancer immunotherapy models including humanized mouse models and syngeneic models*Pro-active attitude and strong desire to contribute to new biology*Strong oral presentation and communication skills*Desire to be part of a team working together to overcome obstacles *Ability to perform complex data analysis*Ability to analyze and interpret work published in the field and use it to place our work in context.*Ability to occasionally travel for work is required.

*EEO & Employment Eligibility*

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

*Senior Scientist, T*
*South San Francisco, California*

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