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Sr. Associate Scientist, Gene Therapy, In Vivo Group


Cambridge, MA
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Job Details

The Gene Therapy Translational Sciences group located in Cambridge, MA is part of Pfizer's Rare Disease Research Unit (RDRU) with a focus on gene therapy specific platform technologies towards the delivery of IND-approved vectors for testing in clinical trials. This Scientist will be part of an interdisciplinary team and contribute to preclinical data required to advance Pfizer's gene therapy-based portfolio.

Job Description

Perform quantitative assessments of AAV gene therapy vectors in tissue biodistribution studies.

Support preclinical tissue distribution, histology, and biochemical assessments studies focused on understanding cellular tropism and efficacy of existing and new gene therapy vectors.

Execute experiments, analyze and interpret data .

Prepare study reports.

Partner with RDRU biology group and other disciplines of integrated drug discovery and development, especially pharmacokinetics and drug disposition, to help prepare translational preclinical packages for gene therapy clinical candidates.

Support aspects of internal and external collaborations and contracted projects.


BS in the life sciences with 2-4 years of academic or industry research experience.

Experience in performing and analyzing in vivo biology assays.

Experience in tissue dissection, processing and high resolution imaging required. Experience with whole tissue clearing (e.g. X-Clarity) and imaging (e.g. Light-Sheet Microscopy) is preferred

Scientific background in the area of stereotactic surgery, human and rodent anatomy

Exceptional communication skills and demonstrated ability to work effectively as part of a team.

Evidence of scientific accomplishments in the form of publications and presentations preferred.

Exceptional communication skills and demonstrated ability to work effectively as part of a team.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**Other Job Details:**

+ **Last Date to Apply for Job:** February 1, 2018

+ Eligible for Employee Referral Bonus: yes

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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