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Sr Scientist Computational Biology, Biomarker Technology

Pfizer


Location:
San Diego, CA
Date:
12/08/2017
2017-12-082018-02-07
Pfizer
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Job Details

**ROLE RESPONSIBILITIES**



The successful candidate will play a critical role in collaborating closely with a translational biomarker lab to develop, implement and validate bio-analytical assays to support clinical trials through:



Conduct computational data analysis on multi-dimensional data generated from various platforms to compare, select as well as troubleshoot and optimize biomarker assays to ensure effective translation of biomarker assays into clinical trials;



Implement bioinformatics pipelines for biomarker assays,contribute to the development of SOPs, and benchmark external and internal platforms and algorithms;



Provide timely bioinformatics support such as data collation, summarization, QC evaluation to support biomarker development efforts



Contribute effectively to a shared codebase that can be leveraged broadly for multiple applications







**QUALIFICATIONS**







+ Ph.D. or equivalent in bioinformatics, computer science or closely related fields with 2-5 years industry or clinical laboratory experience in cancer genomics



+ Demonstrated expertise in data integration and quantitative analysis methods such as machine learning, Bayesian statistics and other bioinformatics algorithms



+ Expertise across various biomarker assay platforms including genomics, epigenetics, and proteins



+ Extensive expertise in common NGS analysis tools and ability to develop and extend computational pipelines for WES/WGS, RNAseq, ChIP-seq and ctDNA



+ Proficiency in R, Matlab, Python and Linux cluster



+ High performance in independent work as well as in a team setting



+ Experience in single-cell data analysis and digital image analysis is a plus







**EEO & Employment Eligibility**



Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.







**Sunshine Act**



Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.







**Other Job Details:**







+ Eligible for Relocation Package



+ Eligible for Employee Referral Bonus







Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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