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Technician, Assay Support, Purification Process Development

Pfizer


Date:
04/05/2018
2018-04-052018-05-06
Pfizer
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Job Details

The St. Louis Culture and Purification Process Development groups of Bioprocess R&D is hiring a technician position to provide laboratory in-process assay support to a diverse team of scientists and engineers focused on developing and optimizing mammalian cell culture processes for recombinant proteins and biologics for early and late phase clinical trials in support of Pfizer's Biotherapeutics portfolio. This role is to seek out directional guidance with in-line assay results and it is not a substitute for Analytical R&DD . In this role the ideal candidate will be responsible for performing critical analytical in-process studies to scientists running both the upstream and downstream processes, with the goal of developing robust, scalable, and productive process that produce therapeutic proteins with the appropriate product quality. The work could also involve working with samples from pilot scale, commercial and clinical production facilities. You may also be involved in cutting edge technology development projects that seek to discover broadly applicable methods to intensify mammalian cell culture.







**ROLE RESPONSIBILITIES**







+ Perform and understand operations of in-process analytical techniques such as routine HPLC assays such as protein A, reverse phase, SECHPLC, SDSPAGE, UPLC, various forms of HPLC, amino acid analysis, spectrophotometry, HCP determination by gyros and or ELISA. Also routine spectrophotometric determination of protein concentrations and an open attitude to developing other relevant analytical skills as required.



+ Additional responsibilities will include Routine maintenance on HPLC, calibrations, troubleshooting equipment, coordinating and/or performing repairs, managing laboratory consumables.



+ Maintaining various electronic databases, maintains equipment/maintenance files, performs quality audits of various analytical instruments.



+ Regularly attending meetings with scientists to analyze and communicate experimental results both orally and in writing.



+ The candidate is also expected to interact with external vendors to solve instrument issues, and internal Site Operations on any facility issues that can affect ongoing operations.



+ The ideal candidate may support scientists in routine process development and analytics understanding of mammalian and bacterial protein process development.



+ Perform all sample preparation and organization.







**BASIC QUALIFICATIONS**







+ HS diploma, Associates Degree, or BS/BA in Biotechnology, Microbiology, Cell Biology, Chemical Engineering, Biochemistry required



+ 1 - 2 years experience in a laboratory or manufacturing environment



+ Demonstrated capability to work as a team member in a matrix development team



+ Strong mechanical aptitude and ability to interface with automated systems



+ Must be capable of generating documents utilizing Microsoft Word and Excel







PREFERRED QUALIFICATIONS







+ Experience in a biological laboratory is desired



+ Understanding of mammalian and bacterial protein process development is highly desirable



+ Ability to work independently and adapt to rapidly changing priorities



+ Ability to be thorough and show great attention to detail



+ Demonstrate quality decision making and effective communication







**NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS**







+ Occasional overtime may be required.







**EEO & Employment Eligibility**



Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.







**Sunshine Act**



Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.







**Other Job Details:**







+ **Last Date to Apply for Job: April 18, 2018**



+ Eligible for Employee Referral Bonus







Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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