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Vice President, Cardiovascular Biology


Cambridge, MA
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Job Details

Job Title Vice President, Cardiovascular Biology

JobID 1033935-1852

Location: Cambridge, MA

Description *About Pfizer*

A career at Pfizer offers opportunity, ownership and impact.All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

*Role Description*

The leader of the Cardiovascular therapeutic area within the Cardiovascular Metabolic (CVMET) Research Unit will be responsible for directing the development of therapies for Cardiovascular disease from early exploratory biology through positive clinical Proof-of-Concept (POC). The successful candidate will be a driver of innovation and scientific excellence, identifying and advancing the best novel therapeutic hypotheses, targets and molecules. This experienced scientific leader will be expected to develop a cardiovascular program within CVMET recognized as a leader in its field by driving and responding to rapidly breaking science and evolving global healthcare demands. *Lead a Therapeutic Area program within the CVMET Research Unit, being responsible for identifying novel targets or pathways to treat key unmet medical needs.*Partner with other disciplines of integrated drug discovery and development, especially chemistry, pharmacokinetics and drug disposition, and clinical, to build a pipeline of clinical candidates with strong and clear rationale for differentiation from standard of care; deliver highly competitive, positive "Proof of Concepts" that fulfill product models aligned to a carefully formulated therapeutic strategy. *Identify and unite emerging science with unmet medical needs. Drive and prosecute a balanced and innovative therapeutic area portfolio of small molecule and biologic based targets, critically prioritized based on rigorous and innovative science. Serve as a role model to Pfizer colleagues by maintaining the highest standards of scientific rigor and ethical principles. Nurture a culture that promotes challenging and respectful interactions among Pfizer colleagues and their external consultants and collaborators.


Strategy: *Set priorities aligned with and integrated into the strategic direction of the RU; serve as a single point of accountability for the delivery of the therapeutic area portfolio from target ID to candidate. *Manage a group of 20 - 30 scientists in the identification of potential targets, the development of small molecules and biologic therapeutics, and basic and clinical discovery research in related scientific areas. *Maintain a detailed and real time perspective of the cardiovascular commercial landscape to inform scientific strategy through understanding areas of unmet need and opportunities for differentiation. *Act as an effective representative of CVMET's investment in cardiovascular disease with key internal and external stakeholders such as the Pfizer Innovative Health organization and the Therapeutic Area Scientific Advisory Panel (TASAP). *Influence the global external environment through a visible presence in the academic scientific community and active engagement with key opinion leaders. *Collaborate with key internal and external biomedical scientists to drive improved understanding of disease pathophysiology to deliver a highly competitive and innovative drug discovery portfolio. *Foster a collaborative and productive environment between Pfizer CVMET RU and academic biomedical researchers. Portfolio: *Deliver a sustainable, highly competitive pipeline from target-to-POC. *Ensure scientific strategy for each drug discovery project is rigorous, aligned and effective. *Interface with senior WRD leaders to balance risk with opportunity, and exploit the full repertoire of therapeutic modalities. . *Prepare reports and presentations as needed describing the progress and strategy of the Cardiovascular unit in CVMET Communication and Management: *Inspire, model, and reinforce colleague expectations to urgently create value with an appropriate return on investment, apply innovative, rigorous science to discovering new medicines, accept individual and collective accountability for value creation, and continuously improve organizational effectiveness. *Build a cohort of colleagues with the quality of scientific leadership and external recognition to generate competitive advantage in attracting the best talent and collaborators. *Engender a high level of engagement across both direct and indirect lines. *Attract and grow highly effective scientists and drug discoverers and nurture a culture that translates breaking biological science into new medicines more effectively than the competition. *Effectively, rigorously and accurately review and develop talent. Proactively address development needs and make difficult decisions when appropriate.


Preferred Training & Education: *Ph.D., M.D. or M.D./Ph.D. *Deep working knowledge of diseases and biology relevant to Cardiovascular Disease. Required Experience: *>15 years' experience as an independent investigator directing a team of scientists in high quality cardiovascular research *Recognized deep biological expertise and record of innovative research in cardiovascular physiology and disease. *Established national and international scientific reputation. Demonstrated track record of high impact publications *Record of team leadership and active, productive collaboration Technical Excellence:*A compelling and inspiring research scientist with a sharp scientific mind, who combines broad knowledge and understanding of biological systems with world-class leadership skills. *Decision making and problem solving profile that enables marrying emerging science with unmet medical need to identify potential breakthrough medicines. *Business "mindset" that teases out and understands risks inherent in drug discovery (small molecule and biotherapeutic), and makes decisions appropriate to opportunity and required investment. *Thinks laterally, connecting seemingly unrelated data, information, perspectives etc, at people, scientific and business levels.

*EEO & Employment Eligibility*

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

*Vice President, Cardiovascular Biology*
*Cambridge, Massachusetts*

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