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VP Early Development Immuno


South San Francisco, CA
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Job Details


The purpose of this position is to:

+ Oversee execution of comprehensive early clinical development strategies for Pfizer Immuno-oncology and oncology discovery assets. Development spans pre-IND, First in patient through Proof of Concept.

+ Work collaboratively across multiple research units to develop integrated clinical portfolio strategies (monotherapy vs combination/adjunctive approaches).

+ Collaborate with key late phase development partners in Pfizer Oncology to align target populations aggressive Proof of Concept plans, allowing for seamless late phase development. Lead early immune-oncology translational medicine strategy and collaborate across research units to drive precision medicine strategy for immune-oncology.

+ Lead early FIP approaches that allow for rapid dose and combination execution.

+ Work collaboratively with multiple research units across Pfizer to drive early Candidate Selection of immuno-oncology early pipeline.

+ Work collaboratively in Immuno-oncology strategic committee to develop integrated immune-oncology strategies.


**Deliver Early Immuno-Oncology Clinical Plans**

The major duties and responsibilities:

+ Develop innovative early clinical development plans that drive early decision making based upon objective clinical safety and efficacy response measures.

+ Introduce early plans in development of combination and/or adjunctive immune-oncology assets.

+ Advise on development concepts in vaccine-based oncology programs.

+ Work collaboratively with Pfizer Oncology to develop expedited Proof of Concept programs that lead to seamless late stage development.

+ Collaborate with external experts to drive innovation in early clinical development plans and translational/precision medicine.

+ Represent Pfizer at critical regulatory interactions.

+ Development of an early immune-oncology clinical investigator network in collaboration with development Operations, to drive rapid early development and decision making.

+ Membership in Biotechnology Clinical Development Technical Review Committee (TRC) and Protocol Review Committee (PRC) to ensure the highest level of rigor and scientific integrity of clinical protocols.

+ Work in partnership with Team Leader(s) to ensure delivery of high-quality, cost-effective programs that are delivered on time and within budget, while maintaining the necessary resources needed to deliver the program.

**Additional responsibilities**

+ Meet regularly with senior leaders, including CSOs on early development issues.

+ Collaboration with Pfizer Business Development and WRD RU leadership to identify new preclinical or pre-PoC candidates and conduct Due Diligence as part of integrated assessments.

+ Identifies and escalate issues in a timely manner as appropriate.

+ Meet with other Pfizer Oncology and Pfizer senior leaders as requested to keep them fully informed of issues of high priority related to department assets.

+ Serve as a member of the EODCR Leadership Team.

+ Work in partnership with Oncology Enterprise leaders to develop an integrated immunotherapy strategy and annual operating plan.


+ Must be a Physician. i.e. MD or MD/PhD with extensive translational/clinical experience.

+ At least 15 years of oncology development experience, with focus in early development and immuno-oncology.

+ Ability to collaborate across multiple organizations in the pre-PoC discovery environment.

+ Ability to lead in a matrixed team environment.

+ Understanding of the drug development continuum from pre-POC to post-POC and commercialization.

+ Understanding of related disciplines (e.g. biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences).

+ Demonstrated scientific productivity (publications, abstracts, etc.).

+ A thorough understanding of immuno-oncology, cancer biology and its relationship to drug development.

+ Experience in functioning effectively as a member of a matrixed, multidisciplinary team with the same dedication to timely delivery of a high quality product.

+ Insight into and understanding of principles related to evaluating business deal structures including commercial collaborations, acquisitions, and divestitures.

+ Experience in budgetary management and decision making.

+ Demonstrated effectiveness in people management, communication and colleague development.

+ Demonstrated effective negotiating and influencing skills, superior interpersonal, leadership, and team player skills.

+ Exceptional verbal and written communication and presentation skills.

+ Ability to collaborate effectively both inside and outside the organization.


Up to 15 within the group

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**Other Job Details:**

+ **Last Date to Apply for Job: 2/23/2018** Additional Location Information: So. San Francisco CA, La Jolla CA,Eligible for Relocation Package - Yes

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.
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